Vaccine associated fibrosarcoma clinical trial for cats.

NORTH CAROLINA
Study: Feline Fibrosarcoma Study
Location: North Carolina State University, Raleigh, NC
Contact: For more information, please call 919-513-8276
http://www.cvm.ncsu.edu/ccmtr/onco2.html

Eligibility: Any cat diagnosed with an injection-site sarcoma or spontaneously arising sarcoma. The biopsy must be place
immediately in a RNA preserving solution.

Summary: Injection-site sarcomas are devastating tumors in cats, which occur at sites of a previous injection or
vaccination. Vaccines were first suspected as an underlying cause of these sarcomas, but other types of injections also
appear to cause the tumors. The laboratory of Dr. Marlene Hauck is evaluating the genetic changes that are seen in these
tumors along with genetics changes seen in spontaneously arising sarcomas and injection site reactions. Our goal is to
identify potential targets for treatment and prevention to improve the outcome for cats with sarcomas. A biopsy sample is
obtained from the sarcoma for the genetic analysis. This can occur at NCSU or at the primary veterinarian.

Requirements and Incentives: There is no financial incentive to take part in this study. We are happy to ship the RNA
preservative solution to any veterinarian performing a biopsy on a cat suspected of one of the above conditions.